at Gleneagles Hospital
Kuala Lumpur

30+years

total clinical
experience

35+years

complex surgical, ASD
& ICU cases supervised

1000+

Trusted Advanced
Stem Cell Therapies

Evidence-based regenerative care for Autism Spectrum Disorder and complex conditions, led by Dr. Chua Kok Seng. We provide medically reviewed, bio-tailored protocols for transformative, long-term results.

International consultations available.

Precision Care

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Take the first step toward a personalized recovery path. Complete our form to secure a clinical consultation with Dr. Chua Kok Seng, where we will evaluate your child’s unique biology and design an evidence-based regenerative strategy for long-term health.
Our medical team will contact you within 24 hours to confirm your appointment.

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Understanding Autism Spectrum Disorder (ASD)

Researches
  • Chronic Neuroinflammation: Ongoing brain inflammation affecting function.
  • Immune Dysregulation: An imbalanced immune response.
  • Altered Neural Signaling: Disruptions in how brain cells communicate.

Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition impacting communication, social interaction, and behavior. Prevalence is rising globally, with the WHO reporting 1 in 100 children and the CDC citing 1 in 36 children diagnosed.

Addressing these underlying biological mechanisms is essential for improving symptom severity and supporting long-term developmental progress.

Modern science reveals that ASD is more than a behavioral condition; it is driven by critical biological factors, including:

The Role of Regenerative Biology in Autism Care

  • Modulating Immune Responses: Rebalancing the body’s natural defenses.
  • Reducing Neuroinflammation: Soothing persistent brain inflammation.
  • Optimizing the Neural Microenvironment: Enhancing the conditions for brain cell communication.

In regenerative medicine, Umbilical Cord-derived Mesenchymal Stem Cells (UC-MSCs) are at the forefront for their potent immune-modulating and neuro-supportive properties.

This biological optimization creates a stronger foundation for the brain, helping children respond more effectively to conventional interventions like behavioral, speech, and educational therapies.

Rather than replacing brain cells, UC-MSC therapy works by:

Scientific Evidence on Stem Cell Therapy for Autism Spectrum Disorder (ASD)

Over the past decade, regenerative medicine has emerged as a promising field in autism research, shifting the focus from behavioral symptoms alone to underlying biological mechanisms. Scientific studies increasingly link Autism Spectrum Disorder (ASD) to factors such as immune dysregulation, chronic neuroinflammation, and altered neural connectivity. In this context, stem cell therapy, particularly mesenchymal stem cells (MSCs), has been investigated for its potential to modulate immune responses, reduce inflammation, and support a healthier neural microenvironment, creating conditions that may enhance developmental outcomes when combined with conventional therapies.

Clinical Outcomes with Umbilical Cord–Derived Mesenchymal Stem Cells (UC-MSCs)

One of the most cited clinical studies, “Transplantation of Human Umbilical Cord Mesenchymal Stem Cells in Autism Spectrum Disorder” by Lv YT et al., published in Cell Transplantation, reported significant improvements in children with ASD following UC-MSC infusions. The study demonstrated a meaningful reduction in CARS scores, alongside observed improvements in social interaction, eye contact, irritability, hyperactivity, and repetitive behaviors. Importantly, no serious neurological adverse events were reported, supporting the safety profile of UC-MSCs under proper clinical supervision. These findings suggest that UC-MSCs may help regulate immune imbalance and neuroinflammation commonly associated with ASD.

Safety, Feasibility, and Broader
Clinical Evidence

Further supporting these findings, a phase I/II study by Dawson G et al., published in Stem Cells Translational Medicine, confirmed that cord blood–based stem cell therapy is safe and well tolerated in young children with autism, with noted improvements in social communication and attention. On a broader scale, a meta-analysis by Wang J et al. in Frontiers in Pediatrics, reviewing data from over 460 patients across 11 studies, reported an average 5–6 point reduction in CARS scores, as well as consistent improvements in ABC and VABS scales, without an increase in serious adverse events. Collectively, these studies reinforce the potential role of stem cell therapy as a supportive, evidence-guided approach in autism care, rather than a standalone cure.

Beyond Autism Spectrum Disorder, stem cell–based regenerative therapy has also been applied in a wide range of complex and age-related conditions. Under the direct medical care of Dr. Chua Kok Seng, regenerative protocols have supported recovery in post-stroke patients, musculoskeletal and bone-related conditions, neurological injuries, as well as cellular anti-aging and long-term health optimization.

Across these clinical applications, Dr. Chua has overseen numerous real-world cases, each managed with careful medical assessment, individualized treatment planning, and ongoing clinical monitoring. The following selected case highlights, supported by clinical imagery and video documentation, illustrate observed functional improvements and recovery trajectories in patients treated under his supervision.

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Regenerative
& Stem Cell Therapy, Delivered with World-Class Clinical Care

  • Under the medical leadership of Dr. Chua Kok Seng, patients can gain access to advanced stem cell and regenerative therapies delivered within internationally accredited clinical settings in Malaysia, supported by Singapore-grade cellular technology and clinical standards. Each treatment pathway is designed to meet rigorous safety, governance, and quality benchmarks.
  • With more than 35 years of clinical experience, Dr. Chua brings an outstanding integration of critical care therapy, regenerative science, and structured medical oversight. His leadership is grounded in careful patient selection, ethical clinical decision-making, and long-term outcome focus – earning the trust of families, medical institutions, and healthcare partners across Malaysia.

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Autism Spectrum Disorder and Stem Cell Therapy: A Regenerative Medicine Approach

  • Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition that affects communication, social interaction, and behavior. Increasing scientific research suggests that ASD is not solely a behavioral condition, but may also be associated with underlying biological mechanisms, including chronic neuroinflammation, immune system dysregulation, and altered neural connectivity.
  • In regenerative medicine, mesenchymal stem cells (MSCs)—especially umbilical cord–derived MSCs (UC-MSCs)—have been studied for their potential role in supporting neurological and immune balance. These cells are known for their ability to modulate immune responses, reduce persistent inflammation, and improve the neural microenvironment, which may help optimize neurological function.
  • Rather than replacing brain cells, stem cell therapy for autism focuses on creating a more favorable biological foundation, allowing the brain to respond more effectively to conventional developmental interventions such as behavioral therapy, speech therapy, and educational support. This integrative approach aligns with current scientific understanding of autism as a condition influenced by both biology and environment.

Advanced Stem Cell Therapy Under Medical Oversight

  • Under the medical leadership of Dr. Chua Kok Seng, patients can gain access to advanced stem cell and regenerative therapies delivered within internationally accredited clinical settings in Malaysia, supported by Singapore-grade cellular technology and clinical standards. Each treatment pathway is designed to meet rigorous safety, governance, and quality benchmarks.
  • With more than 35 years of clinical experience, Dr. Chua brings an outstanding integration of critical care therapy, regenerative science, and structured medical oversight. His leadership is grounded in careful patient selection, ethical clinical decision-making, and long-term outcome focus – earning the trust of families, medical institutions, and healthcare partners across Malaysia.
Consultant Anaesthesiologist, Critical Care
& Regenerative Therapies Specialist

meet Dr. Chua Kok Seng

Dr. Chua is one of Malaysia’s most respected senior physicians, with more than 30 years of service at Gleneagles Hospital Kuala Lumpur (JCI-accredited tertiary hospital) and over 10 years of focused leadership in stem cell and regenerative therapies.
He holds an MBBS from the University of Malaya and is a Fellow of the Faculty of Anaesthetists, Royal College of Surgeons in Ireland (FFARCSI) — a globally recognized credential in perioperative and critical care therapies.
In recent years, Dr. Chua has become a key medical authority in mesenchymal stem cells (MSCs), exosomes, and immune modulation, advising Singapore-based stem cell laboratories and contributing to product development, protocol design, and clinical quality assurance.
MBBS
University of Malaya
DA (UK)
Diploma in Anaesthesia
FFARCSI (Ireland)
Fellow Royal College of Surgeons in Ireland
Registered Specialist 
National Specialist Register, Malaysia
Consultant Anaesthesiologist
Gleneagles Hospital Kuala Lumpur
Umbilical cord–derived mesenchymal stem cells (UC-MSCs) are biologically young stem cells sourced from donated umbilical cords, known for their strong immunomodulatory and anti-inflammatory properties.

Clinical studies such as Lv YT et al., Cell Transplantation and a systematic review published in Frontiers in Pediatrics have reported functional improvements and favorable safety profiles in neurological and developmental conditions, including autism spectrum disorder. Compared to bone marrow–derived stem cells, UC-MSCs demonstrate higher biological activity, lower immunogenicity, and more consistent cell quality.

Under the medical leadership of Dr. Chua Kok Seng, UC-MSC therapies are guided by evidence-based protocols and delivered through close collaboration with Singapore-grade stem cell laboratories. This integrated approach ensures both clinical effectiveness and a high standard of safety in regenerative care.
Portfolio
Consultant Anaesthesiologist, Critical Care
& Regenerative Therapies Specialist

meet Dr. Chua Kok Seng

Dr. Chua Kok Seng is a key medical authority in mesenchymal stem cells (MSCs), exosomes, and immune modulation, with extensive clinical leadership in regenerative medicine, neurological support, and long-term health optimization. With over 30 years of service at Gleneagles Hospital Kuala Lumpur – a JCI-accredited tertiary hospital, he has been directly involved in more than 1,000 complex surgical, critical care, and regenerative treatment cases, including pediatric autism spectrum disorder (ASD), neurological recovery, and wellness-focused regenerative care.
Building on his critical care foundation, Dr. Chua has spent more than a decade advancing the clinical application of stem cell and regenerative therapies. He serves as a medical advisor to Singapore-based stem cell laboratories, contributing to product development, protocol design, and clinical quality governance, ensuring therapies meet international safety and efficacy standards.
MBBS
University of Malaya
DA (UK)
Diploma in Anaesthesia
FFARCSI (Ireland)
Fellow Royal College of Surgeons in Ireland
Registered Specialist 
National Specialist Register, Malaysia
Consultant Anaesthesiologist
Gleneagles Hospital Kuala Lumpur
Medical Education & Credentials

Clinical
& Scientific Credentials

total clinical
experience

35+

years

at Gleneagles Hospital
Kuala Lumpur

30+

years

in regenerative
& stem cell therapies

10+

years

complex surgical, ASD
& ICU cases supervised

1,000+

in exosome-based regenerative therapies

Peer-reviewed research

to Singapore stem cell laboratories

Medical
Advisor

for leading stem cell companies
in Malaysia.

Recognized clinical advisor and thought leader

Areas of Regenerative Expertise

  • Cognitive and behavioral support for autism and neurodevelopmental conditions
  •  Neurological recovery & brain injury support
  •  Immune modulation for complex chronic conditions
  •  Degenerative and inflammatory disorders
  •  Cellular anti-aging & longevity therapies
  • Post-critical illness recovery & functional restoration

His areas of regenerative expertise include:

All therapies are personalized, medically governed, and evidence-guided, delivered under strict clinical oversight to support meaningful and sustainable health outcomes.

Dr. Chua’s clinical practice is dedicated to high-complexity cases and long-term biological optimization, with a particular focus on supporting cognitive, behavioral, and neurological function in children with Autism Spectrum Disorder (ASD) and special developmental needs through evidence-guided regenerative approaches.

Our Regenerative Approach

  • MSCs & Exosomes processed under Singapore-grade quality systems
  • Multi-layer donor screening & biological consistency controls
  • Clinically supervised protocols aligned with Malaysian MOH regulations
  • Continuous outcome monitoring & post-therapy follow-up

Singapore-Standard Cell Technology × Malaysia Clinical Excellence

This integrated model ensures safety, traceability, and biological reliability — critical for high-value, long-term treatments.

Trust & Traction

High-complexity
medical referrals
Trusted by physicians
& medical facilitators
Long-term partnerships with stem cell labs
& hospitals
Regulated, non-experimental regenerative care
Referred by families seeking clinical accountability

Patient Experience

  • Direct medical case review by Dr. Chua
  • Personalized, evidence-guided treatment planning
  • International patient coordination
  • Private clinical settings & continuity of care
  • Privacy, clarity & transparent medical decision-making

Comprehensive Support for International Patients

End-to-end medical coordination designed for clarity, comfort, and peace of mind.
We assist international families with medical invitation letters and visa documentation, coordinating directly with hospitals and relevant authorities to ensure a smooth and timely entry for treatment in Malaysia.
Visa
Support
Access to carefully selected partner hotels located near the treatment center, prioritizing comfort, privacy, and minimal travel time – especially important for children and patients requiring special care.
Hotel
Support
Professional medical interpreters provide 1:1 support throughout consultations, treatment discussions, and follow-up sessions, ensuring clear communication between families and Dr. Chua’s clinical team.
Medical
Translator
Treatment costs are reviewed and explained clearly during the initial medical assessment. All recommendations are evidence-guided and personalized, with full transparency and no unexpected charges beyond the agreed care plan.
Transparent Cost
Estimate

Frequently Asked Questions

Yes. International families receive coordinated support including medical documentation, visa assistance, accommodation guidance, professional medical interpretation, and post-treatment follow-up
Do international patients receive support during treatment in Malaysia?
The consultation includes a comprehensive medical review, evaluation of diagnostic reports, and an in-depth discussion of potential regenerative approaches. Each recommendation is tailored, ethical, and medically justified.
How does the consultation with Dr. Chua take place?
Stem cell therapy is highly personalized. Suitability depends on your medical history, current condition, and treatment goals. A consultation with Dr. Chua ensures that only appropriate, evidence-based regenerative options are recommended.
Is stem cell therapy suitable for everyone?
Yes. All regenerative therapies are customized based on the individual’s condition, treatment complexity, and therapeutic objectives. Transparent guidance is provided after clinical assessment.
Is treatment pricing personalized?
Response timelines vary depending on the condition treated and individual biology. Some patients notice early improvements within weeks, while others experience gradual benefits over several months.
How long does it take to see positive results?
You are encouraged to share prior medical records, imaging results, or laboratory tests if available. Our team will guide you on any additional preparation needed before your session.
Do I need to prepare anything before the consultation?
Stem cell therapy is personalized and guided by clinical evidence. In carefully selected cases, clinical observations suggest that regenerative therapy may support neural function, immune modulation, and developmental progress when integrated with structured medical and educational interventions. Outcomes are monitored over time and may vary based on individual biology and clinical condition.
Can stem cell therapy support children with autism?
Response timelines vary between individuals. Some families report early changes within weeks, while others observe gradual improvements over several months following medically supervised regenerative care.
When can changes be observed in children with autism after stem cell therapy?
Yes. Stem cell therapy is designed to complement—not replace—behavioral, speech, and educational therapies. Combined approaches often lead to more sustainable outcomes.
Do children still need behavioral or speech therapy after stem cell treatment?
Most reported effects are mild and temporary, such as low-grade fever or fatigue. Serious adverse events are rare when therapy is delivered in regulated clinical settings.
Are there any side effects associated with stem cell therapy?

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Dr. Chua Kok Seng

A Deeper Medical Evaluation. A Regenerative Solution in Stem Cell Therapies Designed for You

Access advanced regenerative therapies expertise guided by one of Malaysia’s most experienced specialists.

  • Personalized medical assessment
  •  Evidence-based stem cell strategies
  •  Confidential, one-on-one consultation

Schedule Your Private Consultation with Dr. Chua Today

Book Your Consultation Now

Areas of Regenerative Expertise

  • Neurological recovery and support following brain injury or neurodevelopmental challenges
  • Immune modulation in complex and chronic inflammatory conditions
  • Regenerative support for degenerative and inflammatory disorders
  • Cellular-based anti-aging and longevity therapies
  • Functional recovery following critical illness and intensive care

Dr. Chua’s clinical work is centered on high-complexity medical conditions and long-term biological restoration, with a focus on:

All treatment pathways are individually assessed, evidence-informed, and delivered under strict clinical governance and medical oversight.

Selected Clinical Case Highlights

Children with ASD often present challenges in communication, social engagement and behavior regulation. Under medically supervised regenerative protocols, families have reported improvements in attention, responsiveness and interaction — suggesting supportive effects within a broader neurodevelopmental strategy.
Outcomes vary by individual and are documented under clinical oversight.

A curated selection of real-world clinical cases illustrating functional improvement and recovery trends observed following regenerative interventions. Each case is carefully documented and reviewed under the medical supervision of Dr. Chua Kok Seng.

Advanced Stem Cell
& Regenerative Therapies

Precision - Safety - Longevity

Personalized Regenerative Solutions for Autism Spectrum Disorder, Complex Conditions & Long-Term Health Optimization

Dr. Chua Kok Seng

total clinical
experience

35+years

at Gleneagles Hospital Kuala Lumpur

30+years

complex surgical, ASD
& ICU cases supervised

1,000+